Exploring the Effect of Cytisus Scoparius on Markers of Oxidative Stress in Rats
نویسندگان
چکیده مقاله:
Antioxidant activity of aerial part of Cytisus scoparius, Link (Family Leguminosae) was studied both by in vitro and in vivo models. Different concentrations of different extracts of chloroform, ethyl acetate, methanol and hydroalcoholic extracts of plant were investigated for in vitro antioxidant activity using the thiocyanate method. The hydroalcoholic extract exhibited highest inhibitory activity on peroxidation, over other organic extracts and IC50 value (30.2 g/ml) of the hydroalcoholic extract was found to be less than the standard, a-tocopherol (IC50 value of 66.1g/ml). The hydroalcoholic extract was further evaluated for in vivo antioxidant activity, such as ferric reducing ability of plasma (FRAP), thiobarbituric acid reactive substance (TBARS), superoxide dismutase (SOD), catalase (CAT) and reduced glutathione (GSH). A significant (p < 0.05) rise in FRAP level was observed in the hydroalcoholic extract. The extract showed significant (p < 0.05) reduction of TBARS and increase in SOD enzyme level in liver and kidney. The extract treatment at higher dose only caused a significant (p < 0.05) increase in the level of the catalase in liver and kidney. However, there was no significant effect of TBARS, SOD, and CAT in the heart. In reduced glutathione, the extract did not cause significant changes in liver, heart and kidney. These results suggested that hydroalcoholic extract of Cytisus scoparius had significant antioxidant activity, which supports the claim about the plant to be used as antioxidant in Indian system of medicine.
منابع مشابه
exploring the effect of cytisus scoparius on markers of oxidative stress in rats
antioxidant activity of aerial part of cytisus scoparius, link (family leguminosae) was studied both by in vitro and in vivo models. different concentrations of different extracts of chloroform, ethyl acetate, methanol and hydroalcoholic extracts of plant were investigated for in vitro antioxidant activity using the thiocyanate method. the hydroalcoholic extract exhibited highest inhibitory act...
متن کاملthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است
15 صفحه اولthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
the effect of learning strategies on the speaking ability of iranian students in the context of language institutes
the effect of learning strategies on the speaking ability of iranian students in the context of language institutes abstract language learning strategies are of the most important factors that help language learners to learn a foreign language and how they can deal with the four language skills specifically speaking skill effectively. acknowledging the great impact of learning strategies...
منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 6 شماره 1
صفحات 15- 0
تاریخ انتشار 2007-09
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023